Observation on Therapeutic Effect of Blood-letting Therapy on
Apoplectic Hemiplegia Numbness Syndrome
Liu H, et al. Shanxi Provincial Fenyang Hospital, Shanxi Fenyang 032200, China.
OBJECTIVE: To observe therapeutic effect of blood-letting therapy on apoplectic
hemiplegia numbness syndrome and search for clinically effective therapy.
METHODS: Ninety and five cases of apoplectic hemiplegia were randomly divided
into a treatment group of 55 cases and a control group of 40 cases in order of
visiting. The treatment group were treated with tapping Huatuo Jiaji (EX-B2) on
the back by plum-blossom needle combined with blood-letting on twelve
Well-points or Shixuan (EX-UE 11), once every day, 6 times constituting one
course; the control group were treated with routine acupuncture at points of the
four limbs, once daily, 12 times constituting one course. After they were
treated for 4 courses, their therapeutic effects were observed. RESULTS: The
total effective rate was 94.5% in the treatment group and 77.5% in the control
group with a significant difference between the two groups (P < 0.01).
CONCLUSION: Blood-letting therapy is an effective therapy for post-apoplectic
hemiplegia numbness syndrome.
Zhongguo Zhen Jiu. 2006 May;26(5):337-8.
Acupuncture for Functional Gastrointestinal Disorders
Takahashi T., Department of Surgery, Duke University
Medical Center, Durham, North Carolina, USA.
Functional gastrointestinal (GI) symptoms are common in the general population.
Especially, motor dysfunction of the GI tract and visceral hypersensitivity are
important. Acupuncture has been used to treat GI symptoms in China for thousands
of years. It is conceivable that acupuncture may be effective in patients with
functional GI disorders because it has been shown to alter acid secretion, GI
motility, and visceral pain. Acupuncture at the lower limbs (ST-36) causes
muscle contractions via the somatoparasympathetic pathway, while at the upper
abdomen (CV-12) it causes muscle relaxation via the somatosympathetic pathway.
In some patients with gastroesophageal reflux disease (GERD) and functional
dyspepsia (FD), peristalsis and gastric motility are impaired. The stimulatory
effects of acupuncture at ST-36 on GI motility may be beneficial to patients
with GERD or FD, as well as to those with constipation-predominant irritable
bowel syndrome (IBS), who show delayed colonic transit. In contrast, the
inhibitory effects of acupuncture at CV-12 on GI motility may be beneficial to
patients with diarrhea-predominant IBS, because enhanced colonic motility and
accelerated colonic transit are reported in such patients. Acupuncture at CV-12
may inhibit gastric acid secretion via the somatosympathetic pathway. Thus,
acupuncture may be beneficial to GERD patients. The antiemetic effects of
acupuncture at PC-6 (wrist) may be beneficial to patients with FD, whereas the
antinociceptive effects of acupuncture at PC-6 and ST-36 may be beneficial to
patients with visceral hypersensitivity. In the future, it is expected that
acupuncture will be used in the treatment of patients with functional GI
J Gastroenterol. 2006 May;41(5):408-17.
Uncaria rhynchophylla has Potent Antiaggregation Effects on
Alzheimer's Beta-amyloid Proteins
Fujiwara H, et al. Department of Geriatric and
Complementary Medicine, Center for Asian Traditional Medicine Research, Tohoku
University School of Medicine, Aoba-ku, Sendai, Japan.
Because the deposition of beta-amyloid protein (Abeta)
is a consistent pathological hallmark of Alzheimer's disease (AD) brains,
inhibition of Abeta generation, prevention of Abeta fibril formation, or
destabilization of preformed Abeta fibrils would be attractive therapeutic
strategies for the treatment of AD. We examined the effects of several medicinal
herbs used in traditional Chinese medical formulae on the formation and
destabilization of Abeta fibrils by using the thioflavin T binding assay, atomic
force microscopic imaging, and electrophoresis. Our study demonstrates that
several of these herbs have potent inhibitory effects on fibril formation of
both Abeta(1-40) and Abeta(1-42) in concentration-dependent manners; in
particular, Uncaria rhynchophylla inhibited Abeta aggregation most intensively.
Significant destabilization of preformed Abeta(1-40) and Abeta(1-42) fibrils was
also induced by Uncaria rhynchophylla as well as some other herb extracts.
Three-dimensional HPLC analysis indicated that the water extract of this herb
contains several different chemical compounds, including oxindole and indol
alkaloids, which have been regarded as neuroprotective. Our results suggest that
Uncaria rhynchophylla has remarkably inhibitory effects on the regulation of
Abeta fibrils, and we conclude that this medicinal herb could have the potency
to be a novel therapeutic agent to prevent and/or cure AD. (c) 2006 Wiley-Liss,
J Neurosci Res. 2006 May 4; [Epub ahead of print]