Effects of Different Frequencies of Electro-Acupuncture at Shuigou (GV 26) on Recovery of Motor Function
in Rats with Focal Cerebral Ischemic Injury
Yao WP, et al. Institute of Acupuncture and Moxibustion, The First Affiliated Hospital of Tianjin
University of Traditional Chinese Medicine, Tianjin 300193, China.
OBJECTIVE: To investigate the effects of different frequencies of electro-acupuncture at Shuigou (GV 26) on the latent period and wave amplitude of motor evoked potentials (MEPs) in rats with focal cerebral infarction. METHODS: Fifty healthy male Wistar rats were randomly divided into five groups: controls, model, 2 Hz Shuigou, 50 Hz Shuigou and 100 Hz Shuigou. There were 10 rats in each group. Using a modification of a technique for middle cerebral artery occlusion, focal cerebral ischemic injury was induced in all rats except those in the control group. The rats in the control group received no treatment. After behavioral deficit had been evaluated using the Zausinger 6-point neurological function score, the rats in the Shuigou groups underwent acupuncture and continuous wave stimulation at a frequency of 2 Hz, 50 Hz or 100 Hz (intensity 1 mA) for 10 min twice daily for 3 days. The control and model groups underwent no intervention. Zausinger 6-point neurological function score and MEPs were measured 72 h after the start of treatment. RESULTS: The neurological function scores of the three Shuigou groups were significantly higher than those of the model group (P < 0.05). There was no significant difference between sides in the latency and amplitude of MEPs in the model group (P > 0.05). The latency on the affected side in the model group was significantly longer than that in the control group (P < 0.05) and the amplitude on affected side was significantly reduced (P < 0.01). After 3 days of electro-acupuncture, the latency on the affected side in the 2 Hz Shuigou group was significantly shortened (P < 0.05) and the amplitude was significantly increased (P < 0.05) compared with the model group. CONCLUSION: Low frequency electro-acupuncture at
Shuigou (GV 26) can promote recovery of motor function after
focal cerebral ischemic injury in rats.
J Tradit Chin Med. 2012 Mar;32(1):99-104.
Source: PubMed
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Influence of Acupuncture on Neural Movement Function in Rats with
Middle Cerebral Artery Occlusion
Chang XB, et al. Acupuncture & Moxibustion and Tuina College of Tianjin
University of Traditional Chinese Medicine, Tianjin 300193, China.
OBJECTIVES: To observe recovery in movement function in rats with middle cerebral artery occlusion (MCAO) after acupuncture treatment. METHODS: According to the randomized and controlled principle 1384 rats were divided into the basic control group (including the normal, sham, model control, model without intervention, Nimodipine, and para-Renzhong groups) and the acupuncture group (including the Neiguan (PC 6), Weizhong (BL 40), Sanyinjiao (SP 6), Chize (LU 5), Renzhong (GV 6) and non-acupoint groups). MCAO was modeled by Zea-longa's thread ligation and rats with scores of 1-3, as assessed by Zausinger's six-point method, were used in this study. Moreover, in the acupuncture group each acupoint was set with 12 different parameters by the orthogonal intersection method, resulting in 78 groups with 18 rats per group. The rats were treated by acupuncture once every 12 h for a total of six sessions and neurobehavioral scores were measured after each session. The neurobehavioral scores were compared by one-way ANOVA using the statistical software SPSS 17.0. RESULTS: After acupuncture therapy the mean neurobehavioral scores in MCAO rats increased gradually at each time point with a significant difference among the six scores, but with no significant differences between the fourth (48 h) and the fifth score (60 h), and between the fifth (60 h) and the sixth (72 h) score (P > 0.05). CONCLUSIONS: MCAO rats gradually recovered movement function over multiple acupuncture sessions. After the fouth acupuncture session (48 h), the neurobehavioral scores of rats with cerebral infarction remained stable.
Acupuncture treatment had a reliable curative effect on movement function in
cerebral infarction rats.
J Tradit Chin Med. 2012 Mar;32(1):105-9.
Source: PubMed
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Effects and Possible Mechanisms of Acupuncture at ST36 on Upper and Lower Abdominal Symptoms
Induced by Rectal Distension in Healthy Volunteers
Liu J, et al. 1Wuhan Union Hospital of Huazhong Science & Technology University.
Background Acupuncture (AP) has been shown to have a therapeutic potential for gastrointestinal motility disorders. The aims of this study were to investigate the effects and possible mechanisms of acupuncture on postprandial upper and lower abdominal symptoms induced by rectal distension (RD). Methods: Twelve healthy volunteers were involved in a two-session study (AP and sham-AP). RD was performed for 60 min in the postprandial state and AP at ST36 or sham-AP was performed during the second 30-min period of RD. Gastric slow waves and heart rate variability (HRV) were recorded using the electrogastrogram and electrocardiogram, respectively. Upper and lower abdominal symptoms were scored during RD with AP/sham-AP. In five of the subjects, an additional experiment with two sessions (with AP and no-AP) was performed. Results: 1) RD at an average volume of 171ml induced upper and lower abdominal symptoms (p<0.01). AP but not sham-AP or no-AP reduced both upper and lower abdominal symptoms (p<0.05). 2) RD decreased the percentage of normal gastric slow waves p<0.05). AP improved gastric slow waves in comparison with sham-AP or no-AP (p<0.05). 3) AP but not sham-AP or no-AP significantly increased the vagal activity assessed by the spectral analysis of the HRV (p<0.05). Conclusions: RD induces upper or lower abdominal symptoms and impairs gastric slow waves in healthy volunteers. AP at ST36 is able to improve upper and lower abdominal
symptoms and impaired gastric slow waves induced by RD, possibly mediated
via the vagal pathway.
Am J Physiol Regul Integr Comp Physiol. 2012 May 16.
Source: PubMed
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