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Home > Newsletters > November 2007 > Recent Research

Points - Recent Research

The Effect of Acupuncture on Plasma Endothelin Content in Cerebral Infarction Patients

A Controlled Study on Treatment of Mental Depression by Acupuncture Plus TCM Medication

Yin Chen Hao Tang Inhibits Both Herpes Simplex Virus Type-1 and Type-2 Infections in Vitro


The Effect of Acupuncture on Plasma Endothelin Content in Cerebral Infarction Patients

Yang B, et al. First Hospital Affiliated to Medical College of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, PR China.

OBJECTIVE: To observe the effect of acupuncture on content of plasma endothelin in cerebral infarction patients. METHODS: The plasma endothelin content in cerebral infarction patients was observed before and after acupuncture, which was compared with that of the medication group and the healthy subjects. RESULTS: Before treatment, the content of plasma endothelin in cerebral infarction patients was significantly higher than that of the healthy subjects (P<0.01); after acupuncture treatment, the content greatly decreased (P<0.01), and there was a statistically significant difference between the acupuncture group and the medication group (P<0.05). CONCLUSION: Acupuncture may decrease the content of plasma endothelin in the cerebral infarction patients, improve the vascular elasticity, and improve the cerebral circulation of blood.

J Tradit Chin Med. 2007 Sep;27(3):197-8.

Source PubMed

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A Controlled Study on Treatment of Mental Depression by Acupuncture Plus TCM Medication

He Q, et al. Beijing University of Traditional Chinese Medicine, Beijing 100029, China.

OBJECTIVE: To evaluate the therapeutic effect and safety of acupuncture plus TCM medication for treatment of mental depression. METHOD: 61 cases of mental depression were randomly divided into a treatment group of 30 cases and a control group of 31 cases. The former group was treated by acupuncture plus TCM medication, and the latter with TCM medication alone. The Hamilton Mental Depression (HAMD) scoring system was adopted to evaluate the therapeutic effects, and the Treatment Emergent Symptom Scale (TESS) was used to evaluate the adverse reactions. RESULTS: The treatment group was superior to the control group in the total effective effect (P<0.05), with a significant difference in the HAMD score before and after treatment between the 2 groups (P<0.01). There were marked differences in the reducing rate of HAMD score at the end of the second and sixth week of the treatment between the 2 groups (P<0.05) and the difference was very obvious at the end of the fourth week (P<0.01). No remarkable difference was found in adverse reactions between the 2 groups (P>0.05). CONCLUSION: Acupuncture plus TCM medication may show satisfactory results for mental depression, indicating that a synergic action may exist between acupuncture and TCM medication.

J Tradit Chin Med. 2007 Sep;27(3):166-9.

Source: PubMed

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Yin Chen Hao Tang Inhibits Both Herpes Simplex Virus Type-1 and Type-2 Infections in Vitro

Cheng HY, et al. Department of Cosmetic Applications & Management, Tung Fang Institute of Technology, 829 Kaohsiung County, Taiwan.

Yin Chen Hao Tang (YCHT) is one of the most frequently used prescriptions in the long history of traditional Chinese medicine practice. The prescription contains three Chinese herbs, namely Artemisia capillaries Thunb. (Compositae), Rheum officinale Baillon (Polygonaceae), and Gardenia jasminoids Ellis (Rubiaceae), and has been widely used to treat acute hepatitis with jaundice. In this study, the in vitro anti-HSV-1 and HSV-2 activities of the water extract of YCHT were investigated. Results showed that YCHT water extract inhibited both HSV-1 and HSV-2 infections. However, the inhibition was more effective against HSV-2 than against HSV-1. The IC(50) and IC(90) values of YCHT water extract against HSV-1 infection were in the range of 142.5-150.1 and 191.3-393.9mug/ml, and against HSV-2 infection they were in the range of 19.6-29.4 and 42.2-97.7mug/ml, respectively. The water extract of YCHT showed no cytotoxic effect at a concentration of 500mug/ml or below, and had a CC(50) value of 850.7+/-1.7mug/ml. The prescription was found to diminish HSV-2 infectivity in a dose-dependent manner, and the activity was influenced by the incubation periods and the incubation temperatures. Concurrent addition of virus with YCHT or pre-treatment of the virus with the prescription extract both protected the cells from infection. In summary, the water extract of YCHT was concluded to inhibit infections by HSV-1 and HSV-2 and this effect was likely mediated through direct inactivation of the virus infectivity.

Antiviral Res. 2007 Sep 24; [Epub ahead of print]

Source: PubMed

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