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Home > Newsletters > September 2007 > Recent Research

Points - Recent Research

Acupuncture and Moxibustion Treatment of Chronic Atrophic Gastritis 

Trigger Point Acupuncture Compared with Other Acupuncture for Treatment of Chronic Neck Pain

Effects of Oridonin (Dong Ling Cao) on Proliferation of HT29 Human Colon Carcinoma Cell Lines both in Vitro and in Vivo in Mice


Acupuncture and Moxibustion Treatment of Chronic Atrophic Gastritis

Gao X, et al. Department of Acupuncture and Moxibustion, Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China.

OBJECTIVE: To observe the clinical therapeutic effects of acupuncture and moxibustion in treating chronic atrophic gastritis. METHODS: Patients who met the criteria were randomly divided into the treatment groups consisting of the acupuncture group (30 cases) and the acupuncture-moxibustion group (30 cases), and the control group (28 cases). After two months of treatment, observed were safety and the curative effects, through general physical check ups, routine examinations of blood, urine and feces, and symptoms, pathology and gastrin before, during and after the treatment. RESULTS: (1) The treatment groups showed significant superiorities in the improvement of symptoms, with the acupuncture-moxibustion group showing the best therapeutic effects. (2) The acupuncture-moxibustion group showed marked differences before and after the treatment in the improvement of glandular atrophy and intestinal metaplasia, with a total effective rate of 66.67%. (3) After the treatment, the three groups all showed marked improvement in the level of serum gastrin, with the acupuncture-moxibustion group showing the best effects. CONCLUSION: Acupuncture and moxibustion have definite therapeutic effects for chronic atrophic gastritis, especially in improving the symptoms. Acupuncture or acupuncture combined with moxibustion can provide possibilities in reversing the pathologic changes of glandular atrophy and intestinal metaplasia for patients with chronic atrophic gastritis. Acupuncture-moxibustion is really an effective and safe therapy for chronic atrophic gastritis.

J Tradit Chin Med. 2007 Jun; 27(2):87-91.

Source PubMed

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Trigger Point Acupuncture Compared with Other Acupuncture for Treatment of Chronic Neck Pain

Itoh K, et al. Department of Clinical Acupuncture and Moxibustion, Meiji University of Oriental Medicine, Kyoto 629-0392, Japan.

INTRODUCTION: There is some evidence for the efficacy of acupuncture in chronic neck pain (CNP) treatment, but it remains unclear which acupuncture modes are most effective. Objective was to evaluate the effects of trigger point acupuncture on pain and quality of life (QOL) in CNP patients compared to three other acupuncture treatments (acupoints, non-trigger point and sham treatment). METHODS: Forty out-patients (29 women, 11 men; age range: 47-80 years) from the Department of Orthopaedic Surgery, Meiji University of Oriental Medicine, with non-radiating CNP for at least 6 months and normal neurological examination were randomised to one of four groups over 13 weeks. Each group received two phases of acupuncture treatment with an interval between them. The acupoint group (standard acupuncture; SA, n=10) received treatment at traditional acupoints for neck pain, the trigger point (TrP, n=10) and non-trigger point (non-TrP, n=10) groups received treatment at tenderness points for the same muscle, while the other acupuncture group received sham treatments on the trigger point (SH, n=10). Outcome measures were pain intensity (visual analogue scale; VAS 0-100mm) and disease specific questionnaire (neck disability index; NDI, 60-point scale). RESULTS: After treatment, the TrP group reported less pain intensity and improved QOL compared to the SA or non-TrP group. There was significant reduction in pain intensity between the treatment and the interval for the TrP group (p<0.01, Dunnett's multiple test), but not for the SA or non-TrP group. CONCLUSION: These results suggest that trigger point acupuncture therapy may be more effective on chronic neck pain in aged patients than the standard acupuncture therapy.

Complement Ther Med. 2007 Sep;15(3):172-9. Epub 2006 Jul 10.

Source: PubMed

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Effects of Oridonin (Dong Ling Cao) on Proliferation of HT29 Human Colon Carcinoma Cell Lines both in Vitro and in Vivo in Mice

Zhu Y, et al. Department of Biological Science and Biotechnology, Tsinghua University, Beijing, China.

Oridonin, an active ditepenoid component isolated from Rabdosia rubescens which is currently one of the most important Chinese traditional herbs, has been reported to exhibit anti-tumor effects in vitro. In this study, the anti-proliferation effect of oridonin against the human colorectal carcinoma cells HT29 was investigated both in vitro and in vivo. MTT assay showed that oridonin inhibited HT29 cells in a time- and dose-dependent manner. Flow cytometric analysis demonstrated that oridonin induced a G2/M phase arrest. Apoptotic bodies were observed by Hoechst 32258 fluorescence staining. Notable apoptosis and decrease of mitochondrial membrane potentials was also detected by flow cytometry. In the in vivo experiments, oridonin (10, 15, 20 mg kg(-1) of body weight, on days 1-12) was injected intraperitoneally into mice 24 h after the mice were incubated with HT29 cells. Inhibition of the solid tumor was observed. As a result, oridonin could inhibit the proliferation of HT29 cells both in vitro and in vivo, and induce apoptosis partly via the mitochondrial pathway.

Pharmazie. 2007 Jun;62(6):439-44

Source: PubMed

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