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Home > Research > Anesthesia

Local anesthesia blocks the antiemetic action of P6 acupuncture

By Dundee JW; Ghaly G.

Clinical Pharmacology and Therapeutics, 1991 Jul, 50(1):78-80.
(UI: 91309281)
AT: UCLA Biomed W1 CL681
(PE title: Clinical pharmacology and therapeutics.)

Abstract: The incidence of postoperative illness was monitored for 6 hours in 74 women premedicated with nalbuphine, 10 mg, and undergoing short gynecologic operations of similar duration under methohexitalnitrous oxide-oxygen anesthesia.

Each patient received P6 acupuncture for 5 minutes at the time of administration of premedication. In random order the site of the acupuncture had been previously infiltrated with normal saline solution in half of the patients and 1% lidocaine in the remaining patients.

Postoperative emetic sequelae occurred significantly more often in those who received lidocaine compared with the group that received saline solution.

This demonstrates the ability of a local anesthetic administered at the point of stimulation to block the antiemetic action of P6 acupuncture in a manner similar to that shown by others for analgesia.

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