By Capozza N; Creti c; De Gennaro M; Minni B; Caione P.
[The treatment of nocturnal enuresis. A comparative study between
desmopressin and acupuncture used alone or in combination]
Minerva Pediatrica, 1991 Sep, 43(9):577-82.
AT: UCLA siomed W1 MI558
(PE title: Minerva pediatrica)
Abstract: During the period from March to September 1989, 40 children suffering
from primary nocturnal enuresis, aged between 5 and 14 years, were included
in a study to assess the comparative therapeutical efficacy of DDAVP and
acupuncture. Children were divided into four groups of 10: group A was
treated with DDAVP, group B was treated with acupuncture, group C was
treated with DDAVP and acupuncture and group D was treated with placebo
(control). The trial design included 3 periods: observation (2 weeks),
treatment (8 weeks) and follow-up (4 weeks). Nineteen children completed
the study. The efficacy of treatment, which was expressed as a percentage
of dry nights, was high in both the DDAVP and acupuncture groups, when used
The combined treatment of DDAVP and acupuncture appeared to be
the most efficacious both in terms of the percentage of dry nights at the
end of treatment and in relation to the stability of results, even after
the end of the study. The paper gives a detailed analysis of correlations
between type of treatment and urinary osmolarity.